pair_id	species	ligand_tested	receptor_or_complex_tested	physical_contact_unit	primary_doi	primary_url	figure_or_table	binding_assay	evidence_form	audit_depth	decision	decision_reason	important_boundary
PPR-1	Arabidopsis thaliana	CLV3 mature peptide	CLV1 ectodomain	CLV1 ectodomain	10.1126/science.1150083	https://doi.org/10.1126/science.1150083	original and re-evaluation photoaffinity experiments; figures not accessible in this pass	original CLV3-CLV1 binding assay; later photoaffinity re-evaluation with arabinosylated CLV3	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	do not extend this to every CLE peptide or other CLV receptors
PPR-2	Arabidopsis thaliana	RALF1	FERONIA (FER)	FERONIA (FER)	10.1126/science.1244454	https://doi.org/10.1126/science.1244454	Fig. 4E-F; Supplementary Fig. S18	purified FER ectodomain pull-down with active RALF1; inactive peptide control	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	does not establish all RALFs as FER ligands
PPR-3	Arabidopsis thaliana	CTNIP4 active synthetic peptide	HSL3	HSL3	10.7554/elife.74687	https://doi.org/10.7554/elife.74687	see binding_assay	HSL3 extracellular domain–CTNIP4 ITC, Kd approximately 4 μM; ligand-induced HSL3–BAK1 complex, Fig. 2d–f	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	BAK1 is a co-receptor, not a separate CTNIP4 primary-receptor edge
PPR-4	Arabidopsis thaliana	sulfated CIF2 peptide	GSO1/SGN3	GSO1/SGN3	10.1073/pnas.1911553117	https://doi.org/10.1073/pnas.1911553117	Figs. 1-3	GSO1/SGN3-CIF2 crystal structure, GCI and ITC	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	CIF1 is a separate ligand recorded as PPR-39; GSO2 combinations require independent audit
PPR-5	Solanum lycopersicum	systemin	SYR1	SYR1	10.1038/s41477-018-0106-0	https://doi.org/10.1038/s41477-018-0106-0	Fig. 2	native receptor-specific systemin binding	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	SYR2 is treated separately; SR160/BRI1 and PORK1 are not substituted for SYR1
PPR-6	Triticum aestivum	experimentally synthesized mature DCC1 peptide	DCCR1 extracellular LRR domain	DCCR1 extracellular LRR domain	10.1016/j.xplc.2025.101524	https://doi.org/10.1016/j.xplc.2025.101524	see binding_assay	Competitive TAMRA-DCC1 labeling, Fig. 1K; direct ITC, reported Kd 16 μM, Fig. 1L	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	peptide-level record only—do not assign direct binding separately to every A/B/D precursor
PPR-7	Triticum aestivum	experimentally synthesized mature DCC2 peptide	DCCR1 extracellular LRR domain	DCCR1 extracellular LRR domain	10.1016/j.xplc.2025.101524	https://doi.org/10.1016/j.xplc.2025.101524	see binding_assay	Direct ITC, reported Kd 28 μM, Fig. 1L	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	peptide-level record only, no automatic homoeologue expansion
PPR-8	Arabidopsis thaliana	EPF2	ERECTA–TMM receptor complex	ER-family receptor-TMM complex; do not flatten to isolated receptor	10.1101/gad.179895.111	https://doi.org/10.1101/gad.179895.111	see binding_assay	Purified ER–TMM complex binds EPF2; isolated ER has no detectable binding in the later assay; ERL1–TMM–EPF2 ITC/structure supplies complex-recognition mechanism, Fig. 3–4	receptor-complex binding	original figure/caption or methods audit	admit	EPF2 binds the ER–TMM receptor complex; isolated ER did not bind in the cited complex study.	complex-level edge: TMM forms part of ligand-binding pocket, not an optional decorative modulator
PPR-9	Arabidopsis thaliana	EPF1	ERL1–TMM receptor complex	ER-family receptor-TMM complex; do not flatten to isolated receptor	10.1101/gad.179895.111	https://doi.org/10.1101/gad.179895.111	see binding_assay	EPF1 binds purified ERL1–TMM by ITC, Kd 1.3 μM, and in a 2.63 Å ternary structure, Fig. 3–4; isolated ERL1 shows no detectable binding	receptor-complex binding	original figure/caption or methods audit	admit	EPF1 binds the ERL1–TMM complex; isolated ERL1 did not bind in the cited complex study.	complex-level edge; no isolated-ERL1 binding claim
PPR-10	Arabidopsis thaliana	STOMAGEN/EPFL9	ERECTA–TMM receptor complex	ER-family receptor-TMM complex; do not flatten to isolated receptor	10.1038/nature14561	https://doi.org/10.1038/nature14561	see binding_assay	EPFL9 competes with EPF1/2 for ER-family–TMM binding; ITC shows stronger ERL1–TMM binding than isolated ERL1, Fig. 5	receptor-complex binding	original figure/caption or methods audit	admit	STOMAGEN/EPFL9 binding is recorded for ER–TMM; physiological competition and isolated ER-family affinity are distinct observations.	antagonist/competitive ligand; isolated ERL1 weak binding is reported but receptor complex is physiologically favored
PPR-11	Arabidopsis thaliana	AtPep1	PEPR1 (At1g73080)	PEPR1 (At1g73080)	10.1073/pnas.0603729103	https://doi.org/10.1073/pnas.0603729103	original receptor-identification binding experiments; later receptor–peptide structure	AtPep1–PEPR1 radioligand/photoaffinity binding, with later PEPR1–AtPep1 structural corroboration	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	transgenic tobacco gain-of-function is corroboration, not a native tobacco ligand–receptor edge
PPR-12	Arabidopsis thaliana	CLE19	PXL1	PXL1	10.1038/s41467-023-39074-4	https://doi.org/10.1038/s41467-023-39074-4	Fig. 1b-c	purified PXL1 ectodomain-CLE19 ITC and full-length receptor pull-down	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	SERKs are co-receptors
PPR-13	Arabidopsis thaliana	TDIF mature peptide (CLE41/44-derived; precursor assignment pending)	TDR/PXY	TDR/PXY	10.1371/journal.pone.0175317	https://doi.org/10.1371/journal.pone.0175317	Figs. 1-4	TDR/PXY ectodomain-TDIF crystal structure and ITC	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	peptide-level record, not a separate claim for CLE41 and CLE44 precursor genes
PPR-14	Arabidopsis thaliana	AtSCOOP12	MIK2	MIK2	10.1038/s41477-024-01836-3	https://doi.org/10.1038/s41477-024-01836-3	see binding_assay	Crystal structure of AtMIK2 extracellular domain–AtSCOOP12 complex; biochemical interaction	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	BAK1 is co-receptor; fungal SCOOPL is not a plant-produced ligand
PPR-15	Oryza sativa	OsEPFL5 mature peptide	OsER1	OsER1	10.1016/j.xplc.2024.101204	https://doi.org/10.1016/j.xplc.2024.101204	see binding_assay	ITC and SPR binding to OsER1 extracellular LRR domain, Fig. 2C and Fig. 3C–D; competitive binding, Fig. 3E–F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	antagonist, not interchangeable with OsEPFL6–9 agonists
PPR-16	Oryza sativa	OsEPFL6 mature peptide	OsER1	OsER1	10.1038/s41467-023-37326-x	https://doi.org/10.1038/s41467-023-37326-x	see binding_assay	Direct ITC, Kd 1.35 μM, plus gel filtration, Fig. 3a,e	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	independent SPR confirmation in Guo et al. 2025
PPR-17	Oryza sativa	OsEPFL7 mature peptide	OsER1	OsER1	10.1038/s41467-023-37326-x	https://doi.org/10.1038/s41467-023-37326-x	see binding_assay	Direct ITC, Kd 1.02 μM, plus gel filtration, Fig. 3b,e	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	independently supported competition in Guo et al. 2025
PPR-18	Oryza sativa	OsEPFL8 mature peptide	OsER1	OsER1	10.1038/s41467-023-37326-x	https://doi.org/10.1038/s41467-023-37326-x	see binding_assay	Direct ITC and gel filtration, Fig. 3c,e	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	affinity differs from OsEPFL6/7; do not collapse family members
PPR-19	Oryza sativa	OsEPFL9 mature peptide	OsER1	OsER1	10.1038/s41467-023-37326-x	https://doi.org/10.1038/s41467-023-37326-x	see binding_assay	Direct ITC and gel filtration, Fig. 3d,e	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	independently supported competition in Guo et al. 2025
PPR-20	Arabidopsis thaliana	hydroxyproline-modified IDA dodecamer	HAESA (HAE)	HAESA (HAE)	10.7554/elife.15075	https://doi.org/10.7554/elife.15075	see binding_assay	IDA–HAE ITC and crystal structure, Fig. 1; SERK1 increases affinity	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	HSL2 and other IDL peptides require their own pair-level evidence
PPR-21	Arabidopsis thaliana	AtLURE1.2	PRK6	PRK6	10.1038/s41467-017-01323-8	https://doi.org/10.1038/s41467-017-01323-8	original receptor-recognition figures	PRK6-LURE1.2 purified-domain biochemical binding and structure	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	PRK1/3/8 are not automatically promoted to direct LURE receptors
PPR-22	Triticum aestivum	mature TaCEP15 peptide	TaCEPRL extracellular LRR domain	TaCEPRL extracellular LRR domain	10.1126/sciadv.ady1949	https://doi.org/10.1126/sciadv.ady1949	see binding_assay	Microscale thermophoresis, Kd 1.39 ± 0.94 μM, Fig. 2B	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	do not extend to other wheat CEP/CEPR family members
PPR-23	Zea mays	ZmEPFL1-1	ZmER1	ZmER1	10.1038/s41467-025-67634-3	https://doi.org/10.1038/s41467-025-67634-3	see binding_assay	Purified proteins measured by microscale thermophoresis, Fig. 4a	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	identified in same-species maize material
PPR-24	Zea mays	ZmEPFL1-2	ZmER1	ZmER1	10.1038/s41467-025-67634-3	https://doi.org/10.1038/s41467-025-67634-3	see binding_assay	Microscale thermophoresis, Fig. 4b	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	functional redundancy, not a one-to-one exclusive receptor assignment
PPR-25	Zea mays	ZmEPFL2-1	ZmER1	ZmER1	10.1038/s41467-025-67634-3	https://doi.org/10.1038/s41467-025-67634-3	see binding_assay	Microscale thermophoresis, Fig. 4c	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	functional redundancy
PPR-26	Zea mays	ZmEPFL4-2	ZmER1	ZmER1	10.1038/s41467-025-67634-3	https://doi.org/10.1038/s41467-025-67634-3	see binding_assay	Microscale thermophoresis, strongest binding among five tested peptides, Fig. 4d	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	strongest in assay does not establish dominant physiological sender
PPR-27	Zea mays	ZmEPFL9-1	ZmER1	ZmER1	10.1038/s41467-025-67634-3	https://doi.org/10.1038/s41467-025-67634-3	see binding_assay	Microscale thermophoresis, Fig. 4e; ZmFCP1 negative-control peptide, Fig. 4f	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	weaker affinity but experimentally measured
PPR-28	Arabidopsis thaliana	PIP1	RLK7	RLK7	10.1371/journal.ppat.1004331	https://doi.org/10.1371/journal.ppat.1004331	see binding_assay	Biotin-PIP1 pull-down, chemical crosslinking and radioligand binding, Fig. 7G–I	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	PIP2 response does not by itself establish direct PIP2 binding
PPR-29	Daucus carota	sulfated PSK mature pentapeptide	DcPSKR1	DcPSKR1	10.1038/nature14858	https://doi.org/10.1038/nature14858	see binding_assay	Carrot microsomal affinity purification and island-domain photoaffinity mapping; later PSK–DcPSKR crystal structure and MST binding in Extended Data Fig. 1–2	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	mature-peptide record, carrot precursor gene unresolved
PPR-30	Arabidopsis thaliana	CLE9 mature peptide	BAM1	BAM1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	see binding_assay	Direct CLE9–BAM1 binding; high-affinity ITC and peptide-binding-site tests, Fig. 3	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	distinct from the disputed low-affinity HSL1–CLE9 physiological assignment
PPR-31	Lotus japonicus	triarabinosylated mature CLE-RS2 glycopeptide	HAR1	HAR1	10.1038/ncomms3191	https://doi.org/10.1038/ncomms3191	see binding_assay	[125I]ASA-[Ara3]CLE-RS2 photoaffinity labeling of HAR1, competitor and HAR1-L246F negative controls, Fig. 3a–b	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	preserve glycosylation and mature-peptide identity; do not project to other legume receptors
PPR-32	Arabidopsis thaliana	CEP4 mature peptide	CEPR2	CEPR2	10.1038/s41467-024-55194-x	https://doi.org/10.1038/s41467-024-55194-x	see binding_assay	CEPR2 ectodomain–CEP4 ITC, Kd 15.7 ± 4.5 μM; scrambled-peptide negative control, Fig. 2D–G	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	CEP4–RLK7 is independently tested in Fig. 3 and recorded as PPR-36; CEP4–CEPR1 is not established by this binding assay
PPR-33	Arabidopsis thaliana	CEP1 mature peptide	CEPR2	CEPR2	10.1038/s41467-024-55194-x	https://doi.org/10.1038/s41467-024-55194-x	see binding_assay	CEPR2 ectodomain–CEP1 ITC, Fig. 2F–G	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	peptide specificity is documented separately from CEP4
PPR-34	Triticum aestivum	TaCLE24b synthetic mature peptide (RLSPGGSNPQHH; precursor TraesCS5B02G418500)	TaCLV1 (TraesCS7D02G521200)	TaCLV1 (TraesCS7D02G521200)	10.1038/s41467-025-57291-x	https://doi.org/10.1038/s41467-025-57291-x	see binding_assay	Purified TaCLV1 LRR ectodomain–TaCLE24b MST, Kd 19.35 ± 5.03 nM; TaCEP5 negative control, Fig. 2c	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	receptor genetic test is dosage-limited; do not infer equivalent binding of all TaCLE24 homoeologues
PPR-35	Arabidopsis thaliana	GLV2 mature peptide	RGI3 ectodomain	RGI3 ectodomain	10.15252/embr.202153281	https://doi.org/10.15252/embr.202153281	see binding_assay	Purified RGI3 ECD–GLV2 MST, Kd 129.26 ± 81.69 nM, Fig. 4D	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	BAK1 is a ligand-induced co-receptor and FLS2 an immune-complex partner, not GLV2 primary receptors
PPR-36	Arabidopsis thaliana	CEP4 mature peptide	RLK7	RLK7	10.1038/s41467-024-55194-x	https://doi.org/10.1038/s41467-024-55194-x	see binding_assay	Purified RLK7 ectodomain–CEP4 ITC, Kd 9 ± 4.9 μM, Fig. 3I,L; CEP1 negative control, Fig. 3K	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	CEP4 has multiple receptors; not all CEP4 outputs require RLK7; no CEP1–RLK7 binding detected
PPR-37	Medicago truncatula	fluorescent, biologically active MtCEP1 mature peptide	MtCRA2	MtCRA2	10.1093/jxb/erab244	https://doi.org/10.1093/jxb/erab244	original cross-link and mass-spectrometry experiments	photo-cross-linked FITC-MtCEP1-CRA2 band in native Medicago vascular cells, CRA2 peptides identified by mass spectrometry; cra2 and competition controls	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	tagged-peptide binding in native tissue, not a claim about every CEP peptide or CRA2 orthologue
PPR-38	Oryza sativa	synthetic mature OsRALF4 (precursor LOC_Os12g35670)	THESEUS3/THE3 (LOC_Os06g22810)	THESEUS3/THE3 (LOC_Os06g22810)	10.1038/s41467-026-71645-z	https://doi.org/10.1038/s41467-026-71645-z	see binding_assay	Purified THE3 ectodomain–OsRALF4 MST, Kd 6.1 μM; other rice RALFs tested as comparators, Fig. 5a and Supplementary Fig. 11b	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	OsRALF4 also binds demethylesterified pectin, a distinct extracellular interaction; do not confuse pectin with the receptor
PPR-39	Arabidopsis thaliana	sulfated CIF1 mature peptide	SGN3/GSO1	SGN3/GSO1	10.1073/pnas.1911553117	https://doi.org/10.1073/pnas.1911553117	Fig. 1	GSO1/SGN3-CIF1 GCI/ITC	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	exact binding-assay method and figure to confirm in full text; do not merge with CIF2
PPR-40	Arabidopsis thaliana	bioactive photoaffinity RGF1 analog; unmodified RGF1 competitor	RGFR1 (At3g24240)	RGFR1 (At3g24240)	10.1073/pnas.1522639113	https://doi.org/10.1073/pnas.1522639113	see binding_assay	Covalent [125I]ASA-RGF1 photoaffinity labeling of RGFR1-expressing membranes and displacement by unlabeled RGF1, Fig. 1C–D	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	genetic dependence is shown for receptor family jointly, not uniquely RGFR1 alone
PPR-41	Arabidopsis thaliana	bioactive photoaffinity RGF1 analog; unmodified RGF1 competitor	RGFR2/RCH1 (At5g48940)	RGFR2/RCH1 (At5g48940)	10.1073/pnas.1522639113	https://doi.org/10.1073/pnas.1522639113	see binding_assay	Covalent [125I]ASA-RGF1 labeling of RGFR2-expressing membranes and unlabeled-RGF1 competition, Fig. 1C–D	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	family-level genetic redundancy; no exclusive RGFR2 assignment
PPR-42	Arabidopsis thaliana	bioactive photoaffinity RGF1 analog; unmodified RGF1 competitor	RGFR3 (At4g26540)	RGFR3 (At4g26540)	10.1073/pnas.1522639113	https://doi.org/10.1073/pnas.1522639113	see binding_assay	Covalent [125I]ASA-RGF1 labeling of RGFR3-expressing membranes and unlabeled-RGF1 competition, Fig. 1C–D	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	family-level genetic redundancy; no exclusive RGFR3 assignment
PPR-43	Arabidopsis thaliana	mature AtPep1	PEPR2	PEPR2	10.1105/tpc.109.068874	https://doi.org/10.1105/tpc.109.068874	Figs. 6-7	receptor-expressing membrane photoaffinity labeling, radioligand saturation and competition	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	binding assay uses heterologous expression of the Arabidopsis receptor, but the ligand and receptor are both Arabidopsis; Pep2–PEPR2 requires its own function audit
PPR-44	Arabidopsis thaliana	EPFL4	ERECTA (ER)	ERECTA (ER)	10.1073/pnas.1117537109	https://doi.org/10.1073/pnas.1117537109	see binding_assay	EPFL4 physically associates with ER in planta; purified ER ECD binds EPFL4 without TMM, Fig. 6	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	EPFL4/6 functional redundancy; TMM reduces rather than promotes this binding
PPR-45	Arabidopsis thaliana	EPFL6/CHALLAH	ERECTA (ER)	ERECTA (ER)	10.1073/pnas.1117537109	https://doi.org/10.1073/pnas.1117537109	see binding_assay	EPFL6 physically associates with ER in planta; purified ER ECD binds EPFL6 without TMM, Fig. 6 and Supplementary Fig. 7	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	EPFL4/6 redundancy; do not infer identical behavior of EPFL5 or all ER-family kinases
PPR-46	Arabidopsis thaliana	mature RALF23 peptide	LLG1–FER receptor complex	LLG1 directly binds RALF23; FER joins ligand-dependent complex; isolated FER ECD did not bind	10.1038/s41586-019-1409-7	https://doi.org/10.1038/s41586-019-1409-7	see binding_assay	RALF23 binds purified LLG1 by ITC, whereas isolated FER ectodomain shows no detectable binding; ligand induces LLG1–FER assembly by analytical ultracentrifugation, Fig. 1d–e	receptor-complex binding	original figure/caption or methods audit	admit	RALF23 contacts LLG1; FER is recruited into the ligand-dependent complex. Isolated FER ECD did not bind.	complex-level edge: LLG1 is the measured direct-contact subunit, not isolated FER; LLG2/3 binding is not automatically an in-planta LLG2/3–FER functional edge
PPR-47	Glycine max	GmSubPEP1 mature phytocytokine	GSPR1	GSPR1	10.1038/s41477-026-02375-9	https://doi.org/10.1038/s41477-026-02375-9	see binding_assay	Biotinylated GmSubPEP1 cross-links to soybean GSPR1 expressed in Nicotiana benthamiana, with unlabeled-peptide competition, Fig. 5a; quantitative MST binding, Fig. 5b	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	native soybean response and biochemical binding established; do not infer all GmSubPEP-family pairings
PPR-48	Glycine max	GmSubPEP2 mature phytocytokine	GSPR1	GSPR1	10.1038/s41477-026-02375-9	https://doi.org/10.1038/s41477-026-02375-9	see binding_assay	Biotinylated GmSubPEP2 cross-links to GSPR1 with unlabeled-peptide competition, Fig. 5a; GmSubPEP2–GSPR1 affinity measured by MST, Fig. 5b	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	exact same-species ligand–receptor evidence; GmSubPEP4–GSPR3 remains outside core pending native receptor-loss evidence
PPR-49	Arabidopsis thaliana	RALF4	BUPS1	BUPS1	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3A-C	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-50	Arabidopsis thaliana	RALF4	BUPS2	BUPS2	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3A-C	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-51	Arabidopsis thaliana	RALF4	ANX1	ANX1	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3F-H	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-52	Arabidopsis thaliana	RALF4	ANX2	ANX2	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3F-H	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-53	Arabidopsis thaliana	RALF19	BUPS1	BUPS1	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3A-C	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-54	Arabidopsis thaliana	RALF19	BUPS2	BUPS2	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3A-C	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-55	Arabidopsis thaliana	RALF19	ANX1	ANX1	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3F-H	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-56	Arabidopsis thaliana	RALF19	ANX2	ANX2	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	peptide pull-down and/or MST; Fig. 3F-H	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Each biochemical edge is real; the native genetic phenotype is module-level, not proof that this particular edge is individually necessary.
PPR-57	Arabidopsis thaliana	RALF34	BUPS1	BUPS1	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	biotinylated peptide binding; Fig. 4J-K	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Direct physical recognition is not equivalent to an individually proven receptor-dependent RALF34 response.
PPR-58	Arabidopsis thaliana	RALF34	BUPS2	BUPS2	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	biotinylated peptide binding; Fig. 4J-K	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Direct physical recognition is not equivalent to an individually proven receptor-dependent RALF34 response.
PPR-59	Arabidopsis thaliana	RALF34	ANX1	ANX1	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	biotinylated peptide binding; Fig. 4L-M	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Direct physical recognition is not equivalent to an individually proven receptor-dependent RALF34 response.
PPR-60	Arabidopsis thaliana	RALF34	ANX2	ANX2	10.1126/science.aao3642	https://doi.org/10.1126/science.aao3642	see binding_assay	biotinylated peptide binding; Fig. 4L-M	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Direct physical recognition is not equivalent to an individually proven receptor-dependent RALF34 response.
PPR-61	Zea mays	ZmRALF2	ZmFERL1	ZmFERL1	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-62	Zea mays	ZmRALF2	ZmFERL4	ZmFERL4	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-63	Zea mays	ZmRALF2	ZmFERL7	ZmFERL7	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-64	Zea mays	ZmRALF2	ZmFERL9	ZmFERL9	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-65	Zea mays	ZmRALF3	ZmFERL1	ZmFERL1	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-66	Zea mays	ZmRALF3	ZmFERL4	ZmFERL4	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-67	Zea mays	ZmRALF3	ZmFERL7	ZmFERL7	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-68	Zea mays	ZmRALF3	ZmFERL9	ZmFERL9	10.1093/plcell/koad324	https://doi.org/10.1093/plcell/koad324	see binding_assay	recombinant ECD pull-down and MST; Fig. 5B-F	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Binding differs in strength among FERLs; FERL1 is not pollen-specific. Do not interpret all eight edges as native functional routes.
PPR-69	Brassica napus	BnSCOOP	BnMIK2 ECD	BnMIK2 ECD	10.1038/s41477-024-01836-3	https://doi.org/10.1038/s41477-024-01836-3	see binding_assay	GST-BnSCOOP pull-down of BnMIK2 ECD and BnBAK1 ECD; Fig. 1b	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	No native B. napus receptor-dependent response shown in inspected figures.
PPR-70	Arabidopsis thaliana	IDA	HSL1 ectodomain	HSL1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	Fig. 1a; Supplementary Fig. 2	purified HSL1 ectodomain-IDA/IDL isothermal titration calorimetry	binary receptor binding	original figure/caption or methods audit	admit	Fig. 1a ITC, IDA–HSL1 Kd 400 nM.	SERK1 recruitment occurs after ligand binding; exact in-planta role of each ligand differs
PPR-71	Arabidopsis thaliana	IDL1	HSL1 ectodomain	HSL1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	Fig. 1a; Supplementary Fig. 2	purified HSL1 ectodomain-IDA/IDL isothermal titration calorimetry	binary receptor binding	original figure/caption or methods audit	admit	Fig. 1a ITC, IDL1–HSL1 Kd 590 nM.	SERK1 recruitment occurs after ligand binding; exact in-planta role of each ligand differs
PPR-72	Arabidopsis thaliana	IDL2	HSL1 ectodomain	HSL1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	Fig. 1a; Supplementary Fig. 2	purified HSL1 ectodomain-IDA/IDL isothermal titration calorimetry	binary receptor binding	original figure/caption or methods audit	admit	Fig. 1a ITC, IDL2–HSL1 Kd 121 nM.	SERK1 recruitment occurs after ligand binding; exact in-planta role of each ligand differs
PPR-73	Arabidopsis thaliana	IDL3	HSL1 ectodomain	HSL1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	Fig. 1a; Supplementary Fig. 2	purified HSL1 ectodomain-IDA/IDL isothermal titration calorimetry	binary receptor binding	original figure/caption or methods audit	admit	Fig. 1a ITC, IDL3–HSL1 Kd 690 nM.	SERK1 recruitment occurs after ligand binding; exact in-planta role of each ligand differs
PPR-74	Arabidopsis thaliana	IDL4	HSL1 ectodomain	HSL1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	Fig. 1a; Supplementary Fig. 2	purified HSL1 ectodomain-IDA/IDL isothermal titration calorimetry	binary receptor binding	original figure/caption or methods audit	admit	Fig. 1a ITC, IDL4–HSL1 Kd 2020 nM.	SERK1 recruitment occurs after ligand binding; exact in-planta role of each ligand differs
PPR-75	Arabidopsis thaliana	CLE9	HSL1-SERK1 receptor complex	HSL1-SERK1 complex, not isolated HSL1	10.1038/s41467-022-28558-4	https://doi.org/10.1038/s41467-022-28558-4	Fig. 1a-b; Supplementary Fig. 3	CLE9 binding detected by ITC only in presence of SERK1 (approximately 400 nM); isolated HSL1 negative	receptor-complex binding	original figure/caption or methods audit	admit	CLE9 binding was observed with the HSL1–SERK1 complex; isolated HSL1 was reported as not detectable.	Do not represent as isolated CLE9-HSL1 binding or as unqualified physiological epidermal route
PPR-76	Arabidopsis thaliana	sulfated CIF3	GSO1/SGN3	GSO1/SGN3	10.1073/pnas.1911553117	https://doi.org/10.1073/pnas.1911553117	Fig. 4B	GCI binding to purified receptor ectodomain	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Biochemical binding shown; endogenous CIF3/4 receptor-dependent function not demonstrated
PPR-77	Arabidopsis thaliana	sulfated CIF4	GSO1/SGN3	GSO1/SGN3	10.1073/pnas.1911553117	https://doi.org/10.1073/pnas.1911553117	Fig. 4C	ITC binding to purified receptor ectodomain	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Biochemical binding shown; endogenous CIF3/4 receptor-dependent function not demonstrated
PPR-78	Arabidopsis thaliana	CLE13	BAM1 ectodomain	BAM1	10.1073/pnas.2018565117	https://doi.org/10.1073/pnas.2018565117	Fig. 3E	purified BAM1 ectodomain binding, reported Kd 10 nM	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Do not automatically extend BAM1 result to BAM2 or BAM3
PPR-79	Arabidopsis thaliana	CLE16	BAM1 ectodomain	BAM1	10.1073/pnas.2018565117	https://doi.org/10.1073/pnas.2018565117	Fig. 3E	purified BAM1 ectodomain binding, reported Kd 6.9 nM	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	Do not automatically extend BAM1 result to BAM2 or BAM3
PPR-80	Arabidopsis thaliana	hydroxyproline-modified IDL1	HAESA ectodomain	HAESA	10.7554/eLife.15075	https://doi.org/10.7554/eLife.15075	Fig. 2; Table 2	IDL1-HAESA ITC and co-crystal structure (PDB 5IYN)	binary receptor binding	original figure/caption or methods audit	admit	Exact original-study binding assay recorded in inherited figure-level evidence table.	IDA is the physiological abscission ligand; this row records direct IDL1 biochemical recognition
PPR-81	Arabidopsis thaliana	RGF6	At4g26540 RGF receptor ECD	At4g26540	10.1038/cr.2016.62	https://doi.org/10.1038/cr.2016.62	Supplementary Fig. S2C	purified-receptor microscale thermophoresis; lower affinity than RGF1	binary receptor binding	original supplementary figure S2C image rendered and checked	admit	Supplementary Fig. S2C MST, RGF6–RGFR3 Kd 8930 nM; weak binding, not evidence of signalling.	RGFR numbering differs among 2016 papers; gene ID anchors this receptor. Weaker interaction must not be equated to demonstrated native signaling.
PPR-82	Arabidopsis thaliana	RGF7	At4g26540 RGF receptor ECD	At4g26540	10.1038/cr.2016.62	https://doi.org/10.1038/cr.2016.62	Supplementary Fig. S2C	purified-receptor microscale thermophoresis; lower affinity than RGF1	binary receptor binding	original supplementary figure S2C image rendered and checked	admit	Supplementary Fig. S2C MST, RGF7–RGFR3 Kd 10990 nM; weak binding, not evidence of signalling.	RGFR numbering differs among 2016 papers; gene ID anchors this receptor. Weaker interaction must not be equated to demonstrated native signaling.
PPR-83	Arabidopsis thaliana	RGF9	At4g26540 RGF receptor ECD	At4g26540	10.1038/cr.2016.62	https://doi.org/10.1038/cr.2016.62	Supplementary Fig. S2C	purified-receptor microscale thermophoresis; lower affinity than RGF1	binary receptor binding	original supplementary figure S2C image rendered and checked	admit	Supplementary Fig. S2C MST, RGF9–RGFR3 Kd 6740 nM; weak binding, not evidence of signalling.	RGFR numbering differs among 2016 papers; gene ID anchors this receptor. Weaker interaction must not be equated to demonstrated native signaling.
PPR-84	Brassica rapa	SCR9/SP11-9	SRK9 extracellular domain	SRK9	10.1038/cr.2016.129	https://doi.org/10.1038/cr.2016.129	primary structure and binding figures	crystal structure of the cognate eSRK9-SCR9 complex plus binding-disrupting receptor mutations	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Original abstract explicitly describes SCR9–eSRK9 co-crystal and binding-disruptive mutations; figure not independently rendered.	S-haplotype specific; not a family-wide SCR-SRK edge
PPR-85	Glycine max	GmPEP914	GmP98R1 ectodomain	GmP98R1	10.1038/s41477-025-02086-7	https://doi.org/10.1038/s41477-025-02086-7	Extended Data Fig. 8e-g	original ITC/MST binding assay; receptor-peptide control explicitly named in caption	binary receptor binding	original figure caption; panel image not independently rendered	admit	Original Extended Data Fig. 8e–g caption names GmPEP914–GmP98R1 ITC/MST control; image not independently rendered.	The 63 ROS-matched pairs in Supplementary Table 4 are not automatically physical-binding pairs; this row is the explicitly named GmP98R1-GmPEP914 assay control.
PPR-86	Arabidopsis thaliana	arabinosylated CLV3	BAM1	BAM1	10.1111/tpj.12817	https://doi.org/10.1111/tpj.12817	original photoaffinity experiment; figure not accessible in this pass	photoaffinity labeling of receptor with photoactivatable arabinosylated CLV3	binary receptor binding	assay-explicit original abstract; figure not independently rendered	admit	Original abstract explicitly describes CLV3–BAM1 photoaffinity labelling; figure not independently rendered.	Original paper also found CLV2 and RPK2 did not bind directly; do not add those edges.